It is confirmed in monkey experiments that antibodies that protect the body from new coronavirus are produced by vaccine

An experiment conducted by a research team at the Harvard Medical School on

rhesus monkeys inoculated with a prototype DNA vaccine and a novel coronavirus (SARS-CoV-2) confirmed that the vaccine protects rhesus monkeys from SARS-CoV-2. It was. It is reported that the expectation that this will lead to the development of a new type of coronavirus infectious disease (COVID-19) vaccine for humans is increasing.

DNA vaccine protection against SARS-CoV-2 in rhesus macaques | Science

Immunity to COVID-19 Appears Feasible | Harvard Magazine

Prototype Vaccines Protect Monkeys From Coronavirus |

Monkey trials at Harvard Medical School show promising vaccine results-CBS News

Dan H. Barouch, a professor of medicine at the Harvard Medical School and director of the Virology and Vaccine Research Center at Beth Israel Deacones Medical Center, has a two-step experiment to produce a vaccine with SARS-CoV- Verified to protect rhesus monkey from 2.

In the first experiment, 9 unvaccinated rhesus monkeys were infected with SARS-CoV-2 to see if the rhesus monkeys infected with SARS-CoV-2 produce antibodies. As a result, rhesus monkeys showed moderate COVID-19 symptoms such as pneumonia. Rhesus monkeys recovered from COVID-19 within a few days, so the team examined the rhesus monkey's antibody levels and found that the recovered rhesus monkeys were expressing antibodies to SARS-CoV-2.

Thirty-five days after the SARS-CoV-2 inoculation, when the research team again vaccinated the rhesus monkeys with SARS-CoV-2, the rhesus monkeys did not show COVID-19 symptoms. A test for antibody levels also confirmed that there was a surge of antibodies again in the rhesus monkey.

'If the antibody didn't work well in this experiment, the effort to develop a vaccine would be pointless, which is a nightmare for 7 billion people,' Barouch said. It should have been news like this. '

Based on the results that the rhesus antibody protected rhesus monkeys from SARS-CoV-2, the research team actually created 6 types of vaccines using the SARS-CoV-2 gene. Each vaccine was given to a total of 25 rhesus monkeys, 4-5 each. Then, 3 weeks after the vaccination, I was vaccinated with SARS-CoV-2.

As a result, some vaccines worked poorly, but some did. In particular, 8 out of 25 animals could not detect any trace of SARS-CoV-2 at all.

Barouch said about the results of the two experiments: 'This is very positive news for vaccine development efforts. Further research is needed on whether vaccines and antibodies are effective in humans, but 93% of humans and DNA. Promising results from rhesus macaques that share this will broaden the optimistic view that it is never impossible to make an effective vaccine against COVID-19. '

in Science,   Creature, Posted by log1l_ks